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INI CET 2021 May
T. forsythia is:
• Tannerella forsythia is an anaerobic gram-negative member of the Cytophaga- Bacteroides family.
• Tannerella forsythia is associated more frequently and/or in higher levels with various forms of the disease, including gingivitis, chronic and aggressive periodontitis, than with health.
• Tannerella forsythia has been implicated in the progression of clinical attachment loss associated with periodontitis.
Key concept:
Tannerella forsythia
• Nonmotile, spindle shaped, highly pleomorphic rod
• Gram negative obligate anaerobe
• Grows slowly only in anaerobic conditions and needs several growth factors from other species.
• Produce several proteolytic enzymes that are able to destroy immunoglobulins and factors of the complement system.
• Induces apoptotic cell death.